************OWARI COMPLEX SEMINAR XLV*************

Title  :   Conformational Analysis of Synthesized Antigen for 
         Monoclonal Antibody against Mycobacterium Leprae

Speaker  :  Akihiro Yamane

Affiliation : Mie Chukyo University

Date  :  Tue. Oct. 18th, 3:00 pm (Almost one hour)

Place  :  Seminar Room (4F),
          Graduate School of Information Science

Abstract :
Monoclonal antibody against Mycobacterium leprae was obtained. 
Checking the existence of this antibody let someone know if he was 
infected.  For this object, synthetic antigen PGL1 was obtained 
and has been used as a test agent.  PGL1 which lacks 3- or and 6- 
methyl group, which has  -glucose and or  -rhamnose has less or no 
activity for antibody. The conformational analysis of model 
compound PGL1 using computer has been made, because correlation 
between structure and activity was observed.

***********************************************************